Serum naturally occurring anti-TDP-43 auto-antibodies are increased in amyotrophic lateral sclerosis

Serum naturally occurring anti-TDP-43 auto-antibodies are increased in amyotrophic lateral sclerosis

Abstract Amyotrophic Lateral Sclerosis (ALS) patients express significant clinical heterogeneity that often hinders a correct diagnostic definition. Intracellular deposition of TDP-43, a protein involved in RNA metabolism characterizes the pathology. Interestingly, this protein can be detected in se...

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Main Authors: Elisa Conti, Gessica Sala, Susanna Diamanti, Marco Casati, Christian Lunetta, Francesca Gerardi, Claudia Tarlarini, Lorena Mosca, Nilo Riva, Yuri Falzone, Massimo Filippi, Ildebrando Appollonio, Carlo Ferrarese, Lucio Tremolizzo
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81599-5

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https://doi.org/10.1038/s41598-021-81599-5

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