Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

Synthesis, and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents

A series of twenty new chloropyrazine conjugated benzothiazepines (22–41) have been synthesized with 58%–95% yields. The compounds were characterized by using different spectroscopic techniques including FT-IR, 1H NMR, 13C NMR spectroscopy and mass spectrometry. The synthesized compounds (22–41) and...

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Bibliographic Details
Main Authors: Afzal B. Shaik, Richie R. Bhandare, Srinath Nissankararao, Bontha Venkata Subrahmanya Lokesh, Shaik Shahanaaz, M. Mukhlesur Rahman
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Arabian Journal of Chemistry
Subjects:
Chloropyrazine
Benzothiazepines
Antitubercular
Antimicrobial
Cytotoxic
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535220304767

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http://www.sciencedirect.com/science/article/pii/S1878535220304767

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