Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases
<p>Abstract</p> <p>Background</p> <p>Oncolytic herpes simplex virus (HSV) vectors that specifically replicate in and kill tumor cells sparing normal cells are a promising cancer therapy. Traditionally, recombinant HSV vectors have been generated through homologous recom...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-09-01
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Series: | BMC Biotechnology |
Online Access: | http://www.biomedcentral.com/1472-6750/6/40 |