Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases

Flip-Flop HSV-BAC: bacterial artificial chromosome based system for rapid generation of recombinant herpes simplex virus vectors using two independent site-specific recombinases

<p>Abstract</p> <p>Background</p> <p>Oncolytic herpes simplex virus (HSV) vectors that specifically replicate in and kill tumor cells sparing normal cells are a promising cancer therapy. Traditionally, recombinant HSV vectors have been generated through homologous recom...

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Bibliographic Details
Main Authors: Todo Tomoki, Martuza Robert L, Kuroda Toshihiko, Rabkin Samuel D
Format: Article
Language:English
Published: BMC 2006-09-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/6/40

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http://www.biomedcentral.com/1472-6750/6/40

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