Intrinsic thermal sensing controls proteolysis of Yersinia virulence regulator RovA.

Intrinsic thermal sensing controls proteolysis of Yersinia virulence regulator RovA.

Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts encountered upon host entry lead to a reversi...

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Bibliographic Details
Main Authors: Katharina Herbst, Matthias Bujara, Ann Kathrin Heroven, Wiebke Opitz, Martin Weichert, Ariane Zimmermann, Petra Dersch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2676509?pdf=render

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http://europepmc.org/articles/PMC2676509?pdf=render

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