Tight junction structure, function, and assessment in the critically ill: a systematic review

Tight junction structure, function, and assessment in the critically ill: a systematic review

Abstract Background Epithelial and endothelial barrier integrity, essential for homeostasis, is maintained by cellular boarder structures known as tight junctions (TJs). In critical illness, TJs may become disrupted, resulting in barrier dysfunction manifesting as capillary leak, pulmonary edema, gu...

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Bibliographic Details
Main Authors: David Vermette, Pamela Hu, Michael F Canarie, Melissa Funaro, Janis Glover, Richard W Pierce
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:Intensive Care Medicine Experimental
Subjects:
Tight junctions
Epithelial cells
Endothelial cells
Cellular permeability
Capillary leak
Critical care
Online Access:http://link.springer.com/article/10.1186/s40635-018-0203-4

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http://link.springer.com/article/10.1186/s40635-018-0203-4

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