Zika virus dynamics: Effects of inoculum dose, the innate immune response and viral interference.

Experimental Zika virus infection in non-human primates results in acute viral load dynamics that can be well-described by mathematical models. The inoculum dose that would be received in a natural infection setting is likely lower than the experimental infections and how this difference affects the...

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Bibliographic Details
Main Authors: Katharine Best, Dan H Barouch, Jeremie Guedj, Ruy M Ribeiro, Alan S Perelson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1008564