Compound C, a Broad Kinase Inhibitor Alters Metabolic Fingerprinting of Extra Cellular Matrix Detached Cancer Cells

Compound C, a Broad Kinase Inhibitor Alters Metabolic Fingerprinting of Extra Cellular Matrix Detached Cancer Cells

Most of the cancer related deaths are caused mainly by metastasis. Therefore, it is highly important to unfold the major mechanisms governing metastasis process in cancer. Throughout the metastatic cascade, cells need the ability to survive without attachment to neighboring cells and the original Ex...

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Bibliographic Details
Main Authors: Mohammed Razeeth Shait Mohammed, Raed Ahmed Alghamdi, Abdulaziz Musa Alzahrani, Mazin A. Zamzami, Hani Choudhry, Mohammad Imran Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
AMP-activated protein kinase
metabolomic analysis
extra cellular matrix detachment
compound C
oxidative phosphorylation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.612778/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.612778/full

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