Rab12 Promotes Radioresistance of HPV-Positive Cervical Cancer Cells by Increasing G2/M Arrest

Rab12 Promotes Radioresistance of HPV-Positive Cervical Cancer Cells by Increasing G2/M Arrest

BackgroundHPV-positive (HPV+) cervical cancer cells are more radioresistant compared with HPV-negative (HPV-) cervical cancer cells, but the underlying mechanism is not fully illuminated. Our previous mass spectrometry data showed that Ras-associated binding protein Rab12 was up-regulated by HPV, an...

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Bibliographic Details
Main Authors: Yujie Huang, Yonghao Tian, Wenhao Zhang, Ruijuan Liu, Weifang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
HPV
cervical cancer
radiation
Rab12
G2/M arrest
Cdc2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.586771/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.586771/full

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