Detecting Selection on Protein Stability through Statistical Mechanical Models of Folding and Evolution

The properties of biomolecules depend both on physics and on the evolutionary process that formed them. These two points of view produce a powerful synergism. Physics sets the stage and the constraints that molecular evolution has to obey, and evolutionary theory helps in rationalizing the physical...

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Bibliographic Details
Main Author: Ugo Bastolla
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/4/1/291