Sequence co-evolutionary information is a natural partner to minimally-frustrated models of biomolecular dynamics [version 1; referees: 3 approved]

Experimentally derived structural constraints have been crucial to the implementation of computational models of biomolecular dynamics. For example, not only does crystallography provide essential starting points for molecular simulations but also high-resolution structures permit for parameterizati...

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Bibliographic Details
Main Authors: Jeffrey K Noel, Faruck Morcos, Jose N Onuchic
Format: Article
Language:English
Published: F1000 Research Ltd 2016-01-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/5-106/v1