The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

The transcriptional response to oxidative stress during vertebrate development: effects of tert-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Oxidative stress is an important mechanism of chemical toxicity, contributing to teratogenesis and to cardiovascular and neurodegenerative diseases. Developing animals may be especially sensitive to chemicals causing oxidative stress. The developmental expression and inducibility of anti-oxidant def...

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Bibliographic Details
Main Authors: Mark E Hahn, Andrew G McArthur, Sibel I Karchner, Diana G Franks, Matthew J Jenny, Alicia R Timme-Laragy, John J Stegeman, Bruce R Woodin, Michael J Cipriano, Elwood Linney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4234671?pdf=render

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http://europepmc.org/articles/PMC4234671?pdf=render

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