Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor
The nuclear pregnane X receptor (PXR; NR1I2) is an integral component of the body's defense mechanism against chemical insult (chemoprotection). PXR is activated by a diverse array of lipophilic chemicals, including xenobiotics and endogenous substances, and regulates the expression of cytochro...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2002-03-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520301413 |