First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol

First-in-human clinical trial of transplantation of iPSC-derived NS/PCs in subacute complete spinal cord injury: Study protocol

Introduction: Our group has conducted extensive basic and preclinical studies of the use of human induced pluripotent cell (iPSC)-derived neural stem/progenitor cell (hiPSC-NS/PC) grafts in models of spinal cord injury (SCI). Evidence from animal experiments suggests this approach is safe and effect...

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Main Authors: Keiko Sugai, Miho Sumida, Tomoko Shofuda, Ryo Yamaguchi, Takashi Tamura, Tsuneo Kohzuki, Takayuki Abe, Reo Shibata, Yasuhiro Kamata, Shuhei Ito, Toshiki Okubo, Osahiko Tsuji, Satoshi Nori, Narihito Nagoshi, Shinya Yamanaka, Shin Kawamata, Yonehiro Kanemura, Masaya Nakamura, Hideyuki Okano
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Regenerative Therapy
Subjects:
Induced pluripotent stem cells
Neural stem/progenitor cells
Spinal cord injury
Regenerative medicine
Transplantation
Online Access:http://www.sciencedirect.com/science/article/pii/S235232042100064X

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http://www.sciencedirect.com/science/article/pii/S235232042100064X

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