De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics

De-repressing LncRNA-Targeted Genes to Upregulate Gene Expression: Focus on Small Molecule Therapeutics

Non-protein coding RNAs (ncRNAs) make up the overwhelming majority of transcripts in the genome and have recently gained attention for their complex regulatory role in cells, including the regulation of protein-coding genes. Furthermore, ncRNAs play an important role in normal development and their...

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Bibliographic Details
Main Authors: Roya Pedram Fatemi, Dmitry Velmeshev, Mohammad Ali Faghihi
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
cardiovascular disease
cancer
epigenetics
gene upregulation
long intervening RNAs
long Noncoding RNA
natural antisense transcript
neurological disorders
protein-RNA interactions
RNA structure
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116303456

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http://www.sciencedirect.com/science/article/pii/S2162253116303456

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