Synthesis of Novel <i>Spiro</i>-Tetrahydroquinoline Derivatives and Evaluation of Their Pharmacological Effects on Wound Healing

Synthesis of Novel <i>Spiro</i>-Tetrahydroquinoline Derivatives and Evaluation of Their Pharmacological Effects on Wound Healing

A highly diastereoselective method for the synthesis of novel <i>spiro</i>-tetrahydroquinoline derivatives is reported here, using a one-pot reaction method. All compounds were characterized by <sup>1</sup>H-nuclear magnetic resonance (NMR) and mass spectroscopy, and their st...

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Bibliographic Details
Main Authors: Yan-Cheng Liou, Yan-An Lin, Ke Wang, Juan-Cheng Yang, Yeong-Jiunn Jang, Wenwei Lin, Yang-Chang Wu
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
tetrahydroquinoline
1,3-indandione
<i>spiro</i>-tetrahydroquinoline
one-pot reaction
wound healing
Online Access:https://www.mdpi.com/1422-0067/22/12/6251

Internet

https://www.mdpi.com/1422-0067/22/12/6251

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