Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells

Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells

Abstract Background To determine whether and how exosomes from human umbilical vein endothelial cells (HUVEC-Exos) regulates vascular smooth muscle cells (VSMCs) calcification/senescence in high glucose condition. Methods HUVEC-Exos were isolated from normal glucose (NG) and high glucose (HG) stimul...

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Bibliographic Details
Main Authors: Shuang Li, Jun-Kun Zhan, Yan-Jiao Wang, Xiao Lin, Jia-Yu Zhong, Yi Wang, Pan Tan, Jie-Yu He, Xing-Jun Cui, Yi-Yin Chen, Wu Huang, You-Shuo Liu
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Cell & Bioscience
Subjects:
Vascular smooth muscle cells
Calcification
Aging
Exosomes
VCAN
Mitochondria
Online Access:http://link.springer.com/article/10.1186/s13578-018-0263-x

Internet

http://link.springer.com/article/10.1186/s13578-018-0263-x

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