A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes.

Regulation of iron homeostasis in many pathogens is principally mediated by the ferric uptake regulator, Fur. Since acquisition of iron from the host is essential for the intracellular pathogen Listeria monocytogenes, we predicted the existence of Fur-regulated systems that support infection. We exa...

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Main Authors: Heather P McLaughlin, Qiaobin Xiao, Rosemarie B Rea, Hualiang Pi, Pat G Casey, Trevor Darby, Alain Charbit, Roy D Sleator, Susan A Joyce, Richard E Cowart, Colin Hill, Phillip E Klebba, Cormac G M Gahan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283593?pdf=render