Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons.

Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons.

The Slit protein is a major midline repellent for central nervous system (CNS) axons. In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments, but the biological significance of this is unknown. Analysis in the Drosophila ventral nerve cord of a slit allele (slit-UC) that cannot be...

Full description

Bibliographic Details
Main Authors: Maryam Alavi, Minmin Song, Gracie L Andrews King, Taylor Gillis, Robert Propst, Matthew Lamanuzzi, Adam Bousum, Amanda Miller, Ryan Allen, Thomas Kidd
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC5031454?pdf=render

Internet

http://europepmc.org/articles/PMC5031454?pdf=render

Similar Items