Peripheral blood mononuclear cells of patients with latent autoimmune diabetes secrete higher levels of pro- & anti-inflammatory cytokines compared to those with type-1 diabetes mellitus following in vitro stimulation with β-cell autoantigens

Peripheral blood mononuclear cells of patients with latent autoimmune diabetes secrete higher levels of pro- & anti-inflammatory cytokines compared to those with type-1 diabetes mellitus following in vitro stimulation with β-cell autoantigens

Background & objectives: Type-1 diabetes mellitus (T1DM) and latent autoimmune diabetes in adults (LADA) share similar pathological features but differ in age of onset and progression. There is a scarcity of information on differences in CD4+ T-cell responses, particularly, cytokine secretion, b...

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Bibliographic Details
Main Authors: Darshan Badal, Rajendra Kumar, Mahinder Paul, Devi Dayal, Anil Bhansali, Sanjay Kumar Bhadada, Rajesh Kumar, Naresh Sachdeva
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Indian Journal of Medical Research
Subjects:
CD4+ T-cells - cytokines - glutamic acid decarboxylase 65 - insulin - latent autoimmune diabetes in adults - type-1 diabetes mellitus
Online Access:http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=145;issue=6;spage=767;epage=776;aulast=Badal

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http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2017;volume=145;issue=6;spage=767;epage=776;aulast=Badal

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