Comparative In Vitro Effects of Calcineurin Inhibitors on Functional Vascular Relaxations of Both Rat Thoracic and Abdominal Aorta

Background and Aim. Calcineurin inhibitors (CNIs) have shown to develop hypertension in transplant patients. The in vitro incubation effects of cyclosporine (CsA) and tacrolimus (Tac) on vascular relaxations of rat thoracic aorta (TA) and abdominal aorta (AA) need to be investigated. Methods. The o...

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Bibliographic Details
Main Authors: Ashok Jadhav, Venkat Gopalakrishnan, Ahmed Shoker
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2013/718313