The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the <it>Apc</it><sup>Min/+ </sup>mouse small intestine

The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the <it>Apc</it><sup>Min/+ </sup>mouse small intestine

<p>Abstract</p> <p>Background</p> <p>Alterations in gene splicing occur in human sporadic colorectal cancer (CRC) and may contribute to tumour progression. The K-<it>ras </it>proto-oncogene encodes two splice variants, K-<it>ras </it>4A and 4B, a...

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Bibliographic Details
Main Authors: Berry Rachel L, Devenney Paul S, Walker Marion, Luo Feijun, Rose Lorraine, Arends Mark J, Patek Charles E, Lawrence Nicola J, Ridgway Rachel A, Sansom Owen J, Hooper Martin L
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Gastroenterology
Online Access:http://www.biomedcentral.com/1471-230X/8/24

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http://www.biomedcentral.com/1471-230X/8/24

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