Cytomegalovirus Infection Triggers the Secretion of the PPARγ Agonists 15-Hydroxyeicosatetraenoic Acid (15-HETE) and 13-Hydroxyoctadecadienoic Acid (13-HODE) in Human Cytotrophoblasts and Placental Cultures.

Congenital infection by human cytomegalovirus (HCMV) is a leading cause of congenital abnormalities of the central nervous system. Placenta infection by HCMV allows for viral spread to fetus and may result in intrauterine growth restriction, preeclampsia-like symptoms, or miscarriages. We previously...

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Bibliographic Details
Main Authors: Kaoutar Leghmar, Nicolas Cenac, Maude Rolland, Hélène Martin, Benjamin Rauwel, Justine Bertrand-Michel, Pauline Le Faouder, Mélinda Bénard, Charlotte Casper, Christian Davrinche, Thierry Fournier, Stéphane Chavanas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4501751?pdf=render