Pitavastatin Ameliorates Lipopolysaccharide-Induced Blood-Brain Barrier Dysfunction

Pitavastatin Ameliorates Lipopolysaccharide-Induced Blood-Brain Barrier Dysfunction

Statins have neuroprotective effects on neurological diseases, including a pleiotropic effect possibly related to blood–brain barrier (BBB) function. In this study, we investigated the effects of pitavastatin (PTV) on lipopolysaccharide (LPS)-induced BBB dysfunction in an in vitro BBB model comprisi...

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Bibliographic Details
Main Authors: Takashi Fujimoto, Yoichi Morofuji, Andrej Kovac, Michelle A. Erickson, Mária A. Deli, Masami Niwa, William A. Banks
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
blood-brain barrier
central nervous system diseases
cytokine
inflammation
statin
lipopolysaccharide
Online Access:https://www.mdpi.com/2227-9059/9/7/837

Internet

https://www.mdpi.com/2227-9059/9/7/837

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