Acerogenin A from Acer nikoense Maxim Prevents Oxidative Stress-Induced Neuronal Cell Death through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse Hippocampal HT22 Cell Line

Acerogenin A from Acer nikoense Maxim Prevents Oxidative Stress-Induced Neuronal Cell Death through Nrf2-Mediated Heme Oxygenase-1 Expression in Mouse Hippocampal HT22 Cell Line

Oxidative cell damage contributes to neuronal degeneration in many central nervous system (CNS) diseases such as Parkinson’s disease, Alzheimer’s disease, and ischemia. Inducible heme oxygenase (HO)-1 acts against oxidants that are thought to play a key role in the pathogenesis of neuronal diseases....

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Bibliographic Details
Main Authors: Dong-Sung Lee, Byung-Yoon Cha, Je-Tae Woo, Youn-Chul Kim, Jun-Hyeog Jang
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Molecules
Subjects:
acerogenin A
mouse hippocampal HT22 cells
neuro-protective effects
heme oxygenase-1
nuclear factor-E2-related factor 2
Online Access:http://www.mdpi.com/1420-3049/20/7/12545

Internet

http://www.mdpi.com/1420-3049/20/7/12545

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