The Cystic Fibrosis Transmembrane Regulator (CFTR) in the kidney

The cystic fibrosis transmembrane regulator (CFTR) is a Cl- channel. Mutations of this transporter lead to a defect of chloride secretion by epithelial cells causing the Cystic Fibrosis disease (CF). In spite of the high expression of CFTR in the kidney, patients with CF do not show major renal dysf...

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Bibliographic Details
Main Authors: MARCELO M. MORALES, DORIS FALKENSTEIN, ANÍBAL GIL LOPES
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2000-09-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000300013