The Cystic Fibrosis Transmembrane Regulator (CFTR) in the kidney
The cystic fibrosis transmembrane regulator (CFTR) is a Cl- channel. Mutations of this transporter lead to a defect of chloride secretion by epithelial cells causing the Cystic Fibrosis disease (CF). In spite of the high expression of CFTR in the kidney, patients with CF do not show major renal dysf...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Academia Brasileira de Ciências
2000-09-01
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Series: | Anais da Academia Brasileira de Ciências |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652000000300013 |