The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information

The polygenic risk for bipolar disorder influences brain regional function relating to visual and default state processing of emotional information

Genome-wise association studies have identified a number of common single-nucleotide polymorphisms (SNPs), each of small effect, associated with risk to bipolar disorder (BD). Several risk-conferring SNPs have been individually shown to influence regional brain activation thus linking genetic risk f...

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Bibliographic Details
Main Authors: Danai Dima, Simone de Jong, Gerome Breen, Sophia Frangou
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:NeuroImage: Clinical
Subjects:
Bipolar disorder
Facial affect
fMRI
Polygenic risk score
Visual
Working memory
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158216302030

Internet

http://www.sciencedirect.com/science/article/pii/S2213158216302030

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