Bioavailability of Orally Delivered Alpha-Tocopherol by Poly(Lactic-Co-Glycolic) Acid (PLGA) Nanoparticles and Chitosan Covered PLGA Nanoparticles in F344 Rats

It is hypothesized that the bioavailability of αT (alpha-tocopherol), an antioxidant, can be improved when delivered by poly(lactic-co-glycolic) acid (PLGA) nanoparticles (NPs) and chitosan covered PLGA nanoparticles (PLGA-Chi NPs), and that the mucoadhesive properties of chitosan may enhance absorp...

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Bibliographic Details
Main Authors: Lacey C. Simon, Rhett W. Stout, Cristina Sabliov
Format: Article
Language:English
Published: SAGE Publishing 2016-04-01
Series:Nanobiomedicine
Online Access:https://doi.org/10.5772/63305