Capacity for Seeding and Spreading of Argyrophilic Grain Disease in a Wild-Type Murine Model; Comparisons With Primary Age-Related Tauopathy

Capacity for Seeding and Spreading of Argyrophilic Grain Disease in a Wild-Type Murine Model; Comparisons With Primary Age-Related Tauopathy

Argyrophilic grain disease (AGD) is a common 4R-tauopathy, causing or contributing to cognitive impairment in the elderly. AGD is characterized neuropathologically by pre-tangles in neurons, dendritic swellings called grains, threads, thorn-shaped astrocytes, and coiled bodies in oligodendrocytes in...

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Bibliographic Details
Main Authors: Isidro Ferrer, Pol Andrés-Benito, Julia Sala-Jarque, Vanessa Gil, José Antonio del Rio
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
argyrophilic grain disease
primary age-related tauopathy
tauopathies
tau
seeding
progression
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00101/full

Internet

https://www.frontiersin.org/article/10.3389/fnmol.2020.00101/full

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