Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1.

Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1.

Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Poly(ADP-ribose) polymerase 1 (PARP1) regulates accessibility of chromatin, alters functions of transcriptional activators and repressors, an...

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Bibliographic Details
Main Authors: Michael Hulse, Lisa B Caruso, Jozef Madzo, Yinfei Tan, Sarah Johnson, Italo Tempera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6237423?pdf=render

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http://europepmc.org/articles/PMC6237423?pdf=render

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