Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1.
Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Poly(ADP-ribose) polymerase 1 (PARP1) regulates accessibility of chromatin, alters functions of transcriptional activators and repressors, an...
Main Authors: | Michael Hulse, Lisa B Caruso, Jozef Madzo, Yinfei Tan, Sarah Johnson, Italo Tempera |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-11-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC6237423?pdf=render |
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