Comprehensive and Computable Molecular Diagnostic Panel (C2Dx) From Small Volume Specimens for Precision Oncology: Molecular Subtyping of Non-Small Cell Lung Cancer From Fine Needle Aspirates

Comprehensive and Computable Molecular Diagnostic Panel (C2Dx) From Small Volume Specimens for Precision Oncology: Molecular Subtyping of Non-Small Cell Lung Cancer From Fine Needle Aspirates

The Comprehensive, Computable NanoString Diagnostic gene panel (C2Dx) is a promising solution to address the need for a molecular pathological research and diagnostic tool for precision oncology utilizing small volume tumor specimens. We translate subtyping-related gene expression patterns of Non-Sm...

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Bibliographic Details
Main Authors: Jing Su, Lynn S. Huang, Ryan Barnard, Graham Parks, James Cappellari, Christina Bellinger, Travis Dotson, Lou Craddock, Bharat Prakash, Jonathan Hovda, Hollins Clark, William Jeffrey Petty, Boris Pasche, Michael D. Chan, Lance D. Miller, Jimmy Ruiz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
molecular signature
fine needle aspiration
logistic regression
elastic net regularization
cancer subtyping
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.584896/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.584896/full

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