A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-Type BSE in ovine transgenic mice.

A C-terminal protease-resistant prion fragment distinguishes ovine "CH1641-like" scrapie from bovine classical and L-Type BSE in ovine transgenic mice.

The protease-resistant prion protein (PrP(res)) of a few natural scrapie isolates identified in sheep, reminiscent of the experimental isolate CH1641 derived from a British natural scrapie case, showed partial molecular similarities to ovine bovine spongiform encephalopathy (BSE). Recent discovery o...

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Bibliographic Details
Main Authors: Thierry Baron, Anna Bencsik, Johann Vulin, Anne-Gaëlle Biacabe, Eric Morignat, Jérémy Verchere, Dominique Betemps
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2516186?pdf=render

Internet

http://europepmc.org/articles/PMC2516186?pdf=render

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