Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL

Liver X receptors inhibit human monocyte-derived macrophage foam cell formation by inhibiting fluid-phase pinocytosis of LDL

Liver X receptors (LXRs) are ligand-activated transcription factors involved in the control of lipid metabolism and inflammation. Several studies have recently shown that LXRs promote reverse cholesterol transport and inhibit atherosclerosis. Our study investigated whether LXRs affect macrophage upt...

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Bibliographic Details
Main Authors: Chiara Buono, Yifu Li, Stephen W. Waldo, Howard S. Kruth
Format: Article
Language:English
Published: Elsevier 2007-11-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
cholesterol
endocytosis
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752042440X

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http://www.sciencedirect.com/science/article/pii/S002222752042440X

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