Association of <i>HLA-B*51:01, HLA-B*55:01</i>, <i>CYP2C9*3,</i> and Phenytoin-Induced Cutaneous Adverse Drug Reactions in the South Indian Tamil Population

Association of <i>HLA-B*51:01, HLA-B*55:01</i>, <i>CYP2C9*3,</i> and Phenytoin-Induced Cutaneous Adverse Drug Reactions in the South Indian Tamil Population

Phenytoin (PHT) is one of the most commonly reported aromatic anti-epileptic drugs (AEDs) to cause cutaneous adverse reactions (CADRs), particularly severe cutaneous adverse reactions (SCARs). Although human leukocyte antigen <i>(HLA)-B*15:02</i> is associated with PHT-induced Steven Joh...

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Bibliographic Details
Main Authors: Shobana John, Karuppiah Balakrishnan, Chonlaphat Sukasem, Tharmarajan Chinnathambi Vijay Anand, Bhutorn Canyuk, Sutthiporn Pattharachayakul
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Journal of Personalized Medicine
Subjects:
HLA B
<i>CYP2C9*3</i>
cutaneous adverse drug reactions (CADRs)
anti-epileptic drugs (AEDS)
phenytoin (PHT)
genetic risk factors
Online Access:https://www.mdpi.com/2075-4426/11/8/737

Internet

https://www.mdpi.com/2075-4426/11/8/737

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