RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production

Background/Aims: Viral infections represent a global health problem with the need for new viral therapies and better understanding of the immune response during infection. The most immediate and potent anti-viral defense mechanism is the production of type I interferon (IFN-I) which are activated ra...

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Bibliographic Details
Main Authors: Sathish Kumar Maney, Haifeng C. Xu, Jun Huang, Aleksandra A. Pandyra, Christian Ehlting, Renan Aguilar-Valenzuela, Vitaly I. Pozdeev, David R. McIlwain, Albert Zimmermann, Johannes G. Bode, Hartmut Hengel, Carsten J. Kirschning, Ira R. Kim, John Hiscott, Dirk Brenner, Dieter Häussinger, Pamela S. Ohashi, Tak W. Mak, Karl S. Lang, Philipp A. Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
TLR
Online Access:http://www.karger.com/Article/FullText/447832