A simple method to measure sulfonation in man using paracetamol as probe drug

Abstract Sulfotransferase enzymes (SULT) catalyse sulfoconjugation of drugs, as well as endogenous mediators, gut microbiota metabolites and environmental xenobiotics. To address the limited evidence on sulfonation activity from clinical research, we developed a clinical metabolic phenotyping method...

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Bibliographic Details
Main Authors: Natália Marto, Judit Morello, Alexandra M. M. Antunes, Sofia Azeredo, Emília C. Monteiro, Sofia A. Pereira
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-88393-3