Combination Treatment of Topical Imiquimod Plus Anti-PD-1 Antibody Exerts Significantly Potent Antitumor Effect

Combination Treatment of Topical Imiquimod Plus Anti-PD-1 Antibody Exerts Significantly Potent Antitumor Effect

The exact mechanisms of the imiquimod (IMQ)-induced antitumor effect have not been fully understood. Although both topical IMQ treatment and anti-PD-1 antibody may be used for primary skin lesions or skin metastases of various cancers, the efficacy of each monotherapy for these lesions is insufficie...

Full description

Bibliographic Details
Main Authors: Kazumasa Oya, Yoshiyuki Nakamura, Zhu Zhenjie, Ryota Tanaka, Naoko Okiyama, Yuki Ichimura, Yosuke Ishitsuka, Akimasa Saito, Noriko Kubota, Rei Watanabe, Hideaki Tahara, Manabu Fujimoto, Yasuhiro Fujisawa
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
imiquimod
anti-PD-1 antibody
combination therapy
melanoma
Online Access:https://www.mdpi.com/2072-6694/13/16/3948

Internet

https://www.mdpi.com/2072-6694/13/16/3948

Similar Items