Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells

It is now recognized that small noncoding RNA sequences have the ability to mediate transcriptional activation of specific target genes in human cells. Using bioinformatics analysis and functional screening, we screened short-activating RNA (saRNA) oligonucleotides designed to target the promoter re...

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Bibliographic Details
Main Authors: Jon Voutila, Pål Sætrom, Paul Mintz, Guihua Sun, Jessica Alluin, John J Rossi, Nagy A Habib, Noriyuki Kasahara
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
gene expression profiling
mesenchymal stem cells
pluripotency genes
RNA activation
saRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253116300919

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http://www.sciencedirect.com/science/article/pii/S2162253116300919

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