Cytokinergic IgE action in mast cell activation

Some ten years ago it emerged that at sufficiently high concentrations certain monoclonal mouse IgEs exert previously unsuspected effects on mast cells. Thus they can both promote survival and induce activation of mast cells without the requirement for antigens. This was a wake up call that appears...

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Bibliographic Details
Main Authors: Heather Jane Bax, Anthony Howard Keeble, Hannah Jane Gould
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Immunology
Subjects:
IgE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00229/full