Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study

Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study

Abstract Background To investigate the relationship between early-life stress and glucocorticoid receptor (GR) gene methylation, which may result in long-lasting neurodevelopmental impairment, we performed a longitudinal analysis of the methylation ratio within the GR gene promoter 1F region using n...

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Bibliographic Details
Main Authors: Masato Kantake, Natsuki Ohkawa, Tomohiro Iwasaki, Naho Ikeda, Atsuko Awaji, Nobutomo Saito, Hiromichi Shoji, Toshiaki Shimizu
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Clinical Epigenetics
Subjects:
Adrenal insufficiency
Chronic lung disease
Circulatory collapse
Epigenetics
Glucocorticoid administration
Glucocorticoid receptor gene
Online Access:http://link.springer.com/article/10.1186/s13148-018-0497-9

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http://link.springer.com/article/10.1186/s13148-018-0497-9

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