Inhibitory effect of ginsenoside Rg3 on cancer stemness and mesenchymal transition in breast cancer via regulation of myeloid-derived suppressor cells.

Ginsenoside Rg3 (Rg3) has been studied in several cancer models and is suggested to act through various pharmacological effects. We investigated the anticancer properties of Rg3 through myeloid-derived suppressor cell (MDSC) modulation in FM3A mouse mammary carcinoma cells. The effects of Rg3 on MDS...

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Main Authors: Joong-Hyun Song, Da-Young Eum, Soon-Yong Park, Yun-Ho Jin, Jae-Woong Shim, Shin-Ji Park, Min-Young Kim, Seong-Jun Park, Kyu Heo, Yoo-Jin Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240533