Mathematical Modeling and Analysis of Crosstalk between MAPK Pathway and Smad-Dependent TGF-β Signal Transduction

Broad evidence exists for cross talk between the Mitogen-activated protein kinases (MAPK) pathway and Smad-dependent TGF-β signal transduction. A variety of studies, oftentimes involving different cell types, have identified several potential mechanisms for the crosstalk. However, there is no clear...

Full description

Bibliographic Details
Main Authors: Ji Liu, Wei Dai, Juergen Hahn
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Processes
Subjects:
Online Access:http://www.mdpi.com/2227-9717/2/3/570