Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.

Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.

Various bioactive peptides have been implicated in the homeostasis of organs and tissues. Adrenomedullin (AM) is a peptide with various bioactivities. AM-receptor, calcitonin-receptor-like receptor (CLR) associates with one of the subtypes of the accessory proteins, RAMPs. Among the RAMP subisoforms...

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Bibliographic Details
Main Authors: Ryuichi Uetake, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Yasuhiro Iesato, Takahiro Yoshizawa, Teruhide Koyama, Lei Yang, Yuichi Toriyama, Akihiro Yamauchi, Kyoko Igarashi, Megumu Tanaka, Takashige Kuwabara, Kiyoshi Mori, Motoko Yanagita, Masashi Mukoyama, Takayuki Shindo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914859?pdf=render

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http://europepmc.org/articles/PMC3914859?pdf=render

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