Discrete molecular dynamics can predict helical prestructured motifs in disordered proteins.

Discrete molecular dynamics can predict helical prestructured motifs in disordered proteins.

Intrinsically disordered proteins (IDPs) lack a stable tertiary structure, but their short binding regions termed Pre-Structured Motifs (PreSMo) can form transient secondary structure elements in solution. Although disordered proteins are crucial in many biological processes and designing strategies...

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Bibliographic Details
Main Authors: Dániel Szöllősi, Tamás Horváth, Kyou-Hoon Han, Nikolay V Dokholyan, Péter Tompa, Lajos Kalmár, Tamás Hegedűs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3998973?pdf=render

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http://europepmc.org/articles/PMC3998973?pdf=render

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