Fluorine-containing heterocycles: Part III. Synthesis of some new furo[2,3-b]-, pyrazolo[3,4-b]- and thieno[2,3-b]pyridines with anticipated biological activities

Fluorine-containing heterocycles: Part III. Synthesis of some new furo[2,3-b]-, pyrazolo[3,4-b]- and thieno[2,3-b]pyridines with anticipated biological activities

3-Cyano-6-(2-thienyl)-4-trifluoromethylpyridine-2(1H)-one (1) and its thiono analog 2 were prepared by the reaction of (2-thenoyl)-ω,ω,ω-trifluoroacetone with cyanoacetamide or cyanothioacetamide, respectively. Interaction of compound 1 with ethyl chloroacetate or chloroacetamide led to the regiosel...

Full description

Bibliographic Details
Main Authors: Etify A. Bakhite, Abdu E. Abdel-Rahman, Elham A. Al-Taifi
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Arabian Journal of Chemistry
Subjects:
Furopyridines
Pyrazolopyridines
Thienopyridines
Pyridothienopyrimidines
Pyridothienotriazines
Fluorine-containing compounds
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535214001142

Internet

http://www.sciencedirect.com/science/article/pii/S1878535214001142

Similar Items