Integrin α4β1/VCAM-1 Interaction Evokes Dynamic Cell Aggregation Between Immune Cells and Human Lung Microvascular Endothelial Cells at Infectious Hemolysis

Integrin α4β1/VCAM-1 Interaction Evokes Dynamic Cell Aggregation Between Immune Cells and Human Lung Microvascular Endothelial Cells at Infectious Hemolysis

Bacterial and viral infection is a common cause of pneumonia, respiratory failure, and even acute respiratory distress syndrome. Increasing evidence indicates that red blood cells (RBCs) may contribute to immune response and inflammation. However, the precise molecular mechanisms that link RBC and h...

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Bibliographic Details
Main Authors: Hai-Yan Lou, Hai-Peng Yan, Long-Gui Yang, Jiang-hua Fan, William C. Cho, Zheng-hui Xiao, Shuang-Jie Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
integrin α4β1
methylprednisolone
cell aggregation
red blood cells
dendritic cells
endothelial cells
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.653143/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.653143/full

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