Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

Essential developmental, genomic stability, and tumour suppressor functions of the mouse orthologue of hSSB1/NABP2.

Single-stranded DNA binding proteins (SSBs) regulate multiple DNA transactions, including replication, transcription, and repair. We recently identified SSB1 as a novel protein critical for the initiation of ATM signaling and DNA double-strand break repair by homologous recombination. Here we report...

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Bibliographic Details
Main Authors: Wei Shi, Amanda L Bain, Bjoern Schwer, Fares Al-Ejeh, Corey Smith, Lee Wong, Hua Chai, Mariska S Miranda, Uda Ho, Makoto Kawaguchi, Yutaka Miura, John W Finnie, Meaghan Wall, Jörg Heierhorst, Carol Wicking, Kevin J Spring, Frederick W Alt, Kum Kum Khanna
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3567186?pdf=render

Internet

http://europepmc.org/articles/PMC3567186?pdf=render

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