Abolition of peroxiredoxin-5 mitochondrial targeting during canid evolution.

In human, the subcellular targeting of peroxiredoxin-5 (PRDX5), a thioredoxin peroxidase, is dependent on the use of multiple alternative transcription start sites and two alternative in-frame translation initiation sites, which determine whether or not the region encoding a mitochondrial targeting...

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Bibliographic Details
Main Authors: Valérie Van der Eecken, André Clippe, Sophie Dekoninck, Julie Goemaere, Geoffroy Walbrecq, Paul P Van Veldhoven, Bernard Knoops
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759418?pdf=render