Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury.

Early systemic granulocyte-colony stimulating factor treatment attenuates neuropathic pain after peripheral nerve injury.

Recent studies have shown that opioid treatment can reduce pro-inflammatory cytokine production and counteract various neuropathic pain syndromes. Granulocyte colony-stimulating factor (G-CSF) can promote immune cell differentiation by increasing leukocytes (mainly opioid-containing polymorphonuclea...

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Bibliographic Details
Main Authors: Po-Kuan Chao, Kwok-Tung Lu, Yun-Lin Lee, Jin-Chung Chen, Hung-Li Wang, Yi-Ling Yang, Mei-Yun Cheng, Ming-Feng Liao, Long-Sun Ro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3427178?pdf=render

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http://europepmc.org/articles/PMC3427178?pdf=render

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