Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice

Combined Omics Reveals That Disruption of the Selenocysteine Lyase Gene Affects Amino Acid Pathways in Mice

Selenium is a nonmetal trace element that is critical for several redox reactions and utilized to produce the amino acid selenocysteine (Sec), which can be incorporated into selenoproteins. Selenocysteine lyase (SCL) is an enzyme which decomposes Sec into selenide and alanine, releasing the selenide...

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Bibliographic Details
Main Authors: Lucia A. Seale, Vedbar S. Khadka, Mark Menor, Guoxiang Xie, Ligia M. Watanabe, Alexandru Sasuclark, Kyrillos Guirguis, Herena Y. Ha, Ann C. Hashimoto, Karolina Peplowska, Maarit Tiirikainen, Wei Jia, Marla J. Berry, Youping Deng
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Nutrients
Subjects:
metabolomics
selenium
transcriptomics
liver
selenocysteine
lyases
Online Access:https://www.mdpi.com/2072-6643/11/11/2584

Internet

https://www.mdpi.com/2072-6643/11/11/2584

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